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A Woman's Center For Reproductive Medicine Team of Fertility Doctors and Specialists
 
 
 


Clomid, Serophene, (Clomiphene Citrate)

Clomid works at the hypothalamus in contrast to FSH, which directly stimulates the ovaries. The hypothalamus can be thought of as a thermostat, controlling the interaction of various reproductive hormones. It produces gonadotropin releasing hormone, which stimulates the pituitary to produce FSH and LH.

As follicles develop, they produce estrogen, which travels through the bloodstream to the hypothalamus. The hypothalamus monitors the estrogen levels and adjusts the production of FSH accordingly. As estrogen increases, signaling follicular development, FSH production slows. Clomid binds the estrogen receptors at the hypothalamus making it read lower levels of estrogen than actually exist thereby increasing FSH production.

In contrast to FSH, once ovulation is occurring regularly on Clomid, there is no advantage to increasing the dose. Studies clearly show that pregnancy from Clomid use is most likely to result during the first three cycles. Our fertility specialists rarely extend Clomid use beyond three to six ovulatory cycles.

Intrauterine insemination (IUI) after stimulation with FSH is sometimes the second treatment step. Fertility treatments are individualized for each couple and the one most likely to result in pregnancy is always chosen. Our fertility specialists consider many factors such as the cause(s) of a couple's infertility, previous treatment history, response to medications, presence of male infertility, and many other factors.

Many of our fertility clinic patients live and work in New Orleans, LA but travel to Baton Rouge for treatment. We have established an excellent reputation for the highest quality of service and patients' appreciate our compassionate and caring staff.

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