Progesterone

After ovulation the "spent" follicle forms a structure known as the corpus luteum. The corpus luteum produces progesterone to help support endometrial development critical to the developing fetus. The placenta is formed after the embryo embeds in the endometrial lining and it also produces progesterone.

Increases in progesterone levels are a good indication that ovulation has occurred since the corpus luteum must have formed. Progesterone is given in virtually all IVF cycles because Lupron and Antagon interfere with the body's natural production.

Progesterone is also effective in correcting a "luteal phase defect". This occurs when the body does not produce enough progesterone to adequately support the endometrium. Additional progesterone insures that the endometrium develops to the point where it can support the embryo and fetus.

Progesterone is administered by oral troches, vaginal suppositories, as a gel, oral micronized capsules, or injection.

 

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